Miconazole Nitrate Nanocrystals Combined with Chlorhexidine Digluconate for Improved Treatment of Fungal Skin Diseases

نویسندگان

  • S. M. Pyo
  • D. Hespeler
  • C. M. Keck
  • R. H. Mueller
چکیده

منابع مشابه

Residual antibacterial activity of canine hair treated with topical antimicrobial sprays against Staphylococcus pseudintermedius in vitro.

BACKGROUND Topical antimicrobial therapy is increasingly important in the treatment of canine pyoderma as the incidence of multidrug resistance has risen. However, little information is reported on the persistence of activity of topical antimicrobial products. OBJECTIVE To determine the residual antibacterial activity of canine hairs treated with antimicrobial sprays. ANIMALS Twelve private...

متن کامل

Preparation and In Vitro Evaluation of Miconazole Nitrate–Loaded Topical Liposomes

nitrate is a widely used antifungal agent, but its use in topical formulations is not efficacious because deepseated fungal infections are difficult to treat with conventional topical formulations. The entrapment of a drug in liposomes can facilitate localized delivery of the drug, and improved availability by means of a controlled-release pattern can advance the treatment of deep fungal infect...

متن کامل

Design, Optimization and Characterization of a Transfersomal Gel Using Miconazole Nitrate for the Treatment of Candida Skin Infections

Miconazole nitrate (MIC) is an antifungal drug used for treatment of superficial fungal infections. However, it has low skin permeability. Hence, the objective of this study was to prepare miconazole nitrate using Transfersomes to overcome the barrier function of the skin. MIC Transfersomes were prepared using a thin lipid film hydration technique. The prepared Transfersomes were evaluated with...

متن کامل

Solubility Enhancement of Miconazole Nitrate for Formulation and Evaluation of Mucoadhesive Gel

The goal of the present investigation is formulation and evaluation of a mucoadhesive gel for buccal delivery after solubility enhancement of very slightly water-soluble drug Miconazole Nitrate. Miconazole Nitrate is imidazole derivative useful in treatment of oropharyngeal Candidiasis, the most common infection in AIDS patients. The method namely solvent deposition with inclusion complex, soli...

متن کامل

Candida albicans survival, growth and biofilm formation are differently affected by mouthwashes: an in vitro study.

Candida albicans is the most common cause of oral mycoses. The aim of the present study was to investigate in vitro the susceptibility of C. albicans to mouthwashes, in terms of growth, survival and biofilm formation. Candida albicans, laboratory strain SC5314, and 7 commercial mouthwashes were employed: 3 with 0.2% chlorhexidine digluconate; 1 with 0.06% chlorhexidine digluconate and 250 ppm F...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

متن کامل
عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016